Does a 2 microliter example guarantee every sample can be measured that way?
No. Confirm the supported arrangement and evaluate the actual dispersion. A small reference-sample demonstration does not establish suitability for every material or matrix.
The small-drop demonstration used a polystyrene reference suspension and compared specified volumes and dilution conditions. Treat that evidence as a defined example rather than a guarantee for every protein, formulation or solvent. Sample condition, probe coverage and the available analytical quantity belong in the method discussion.
How closely did a 2 µL drop match the immersion measurement?
Microtrac tested a nominal 400 nm polystyrene suspension by placing a drop on the center of an inverted NANOTRAC FLEX probe. The undiluted 2 µL drop gave a D50 of 393 nm. The 5 µL drop and the immersed probe each gave 402 nm for that suspension.
Method details to record
| Consideration | What to record |
|---|---|
| Available quantity | Usable volume and reserve needs |
| Dispersion state | Concentration and sample medium |
| Measurement comparison | Reference or established method |
How should a limited-volume formulation be evaluated?
Compare the drop arrangement with a compatible immersion measurement on representative material when enough sample is available. Record the volume, medium, dilution, probe coverage and distribution basis. Changing the liquid or concentration can change the dispersion itself.
Explore particle characterization equipment
Review the equipment details and discuss the supported configuration for your sample.