Can a stable size distribution alone establish shelf life?
No. Size is one observation. Evaluate interaction conditions and the relevant changes over time before interpreting the formulation's physical stability.
A formulation change may alter interactions before a large size change becomes visible, while physical separation can occur for reasons not resolved by charge alone. Plan complementary measurements around the product and the time-dependent behavior being studied. Microtrac NANOTRAC, STABINO ZETA and TURBISCAN workflows address different parts of that investigation.
Planning zeta potential and dispersion stability
Specify the formulation environment and the change being investigated. Size, charge-related behavior and physical separation are complementary observations. Evaluate them within a controlled comparison over the relevant conditions rather than interpreting one measurement as a universal prediction of product stability.
What to bring to an application discussion
| Consideration | Information to provide |
|---|---|
| Formulation context | Composition and liquid environment |
| Measurement set | Size, charge and physical stability |
| Comparison design | Time and controlled formulation changes |
Questions before selecting a configuration
How can Glen Mills help with this application?
Share formulation context, measurement set, comparison design when you contact Glen Mills for further information or a quote. This helps focus the discussion on the preparation and evaluation described here.
How should a measurement result be assessed?
Use the size definition, distribution basis and acceptance criteria required by your measurement method. Discuss particle measurement with Glen Mills when a representative trial is needed to evaluate the configuration.
Explore particle characterization equipment
Review the equipment details and discuss the supported configuration for your sample.